Head of Medicinal Chemistry

Natick, Massachusetts

Position closed

Allorion Therapeutics is seeking a highly motivated and experienced leader as Head of Medicinal Chemistry to lead medicinal chemistry team within a dynamic and interdisciplinary team of junior or senior scientists to develop new therapeutics for unmet medical needs. The successful candidate will be a key member of the Allorion leadership team and responsible for ensuring the strategic planning and execution of clinical development within timelines and budgets and with high qualities.

  • Lead Allorion medicinal chemistry team across multiple programs
  • Overview all programs up to IND-enabling studies, including structure-based drug design
  • Provide scientific direction, leadership and solution for medicinal chemistry and synthetic
    chemistry activities of Allorion
  • Work across a matrixed organization with Discovery Biology, Translational Medicine,
    DMPK/clinic pharm, Tox, and CMC to deliver the candidate compound within a suitable timeline
  • Provide strategic perspective and guidance to Allorion’s R&D for discussions and decisions with
    Allorion management team
  • Overview synthetic chemistry activities at in-house and Contract Research Organizations (CROs)
  • PhD with strong chemistry research background
  • 15+ years of industry experience with 5+ years in leading medicinal chemistry group, with
    demonstrated track records in delivering clinical candidates within a suitable timeline and
  • Able to provide leadership on a medicinal chemistry team and cross-functional team
  • Strong organizational skills and the ability to manage multiple tasks
  • Ability to thrive in the highly entrepreneurial biotech environment, with experience in a
    small/medium size company
  • Excellent interpersonal skills and mindset of collaboration and teamwork, and the ability to
    function in a highly matrixed organization